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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $52.70 | Total: $263.50 |
| 1 | 10 | $44.64 | Total: $446.40 |
| 1 | 25 | $37.82 | Total: $945.50 |
| 1 | 50 | $32.24 | Total: $1,612.00 |
| 1 | 100 | $27.90 | Total: $2,790.00 |
Overview
DuP-697 is an irreversible and specific inhibitor of COX-2 with IC50 values of 10 nM and 800 nM for human COX-2 and COX-1. DuP-697 shows antiproliferative activity with an IC50 of 42.8 nM. DuP-697 exhibits antiangiogenic, anti-inflammatory, antipyretic and apoptotic effects.
Chemical Properties
| Molecular Formula | C17H12BrFO2S2 |
| Molecular Weight | 411.31 |
| CAS Numbers | 88149-94-4 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CS(=O)(=O)c1ccc(cc1)-c1cc(Br)sc1-c1ccc(F)cc1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Altun A, et al. Anticancer effect of COX-2 inhibitor DuP-697 alone and in combination with tyrosine kinase inhibitor [E7080] on colon cancer cell lines. Asian Pac J Cancer Prev. 2014;15[7] 3113-21.