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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $211.65 | Total: $1,058.25 |
| 1 | 10 | $179.28 | Total: $1,792.80 |
| 1 | 25 | $151.89 | Total: $3,797.25 |
| 1 | 50 | $129.48 | Total: $6,474.00 |
| 1 | 100 | $112.05 | Total: $11,205.00 |
Overview
CBS9106 (SL-801) is a reversible oral CRM1 inhibitor with CRM1 degrading and antitumor activity.CBS9106 inhibits CRM1-dependent nuclear export and reduces CRM1 protein levels.CBS9106 inhibits tumor growth and prolongs the survival of mice bearing tumor xenografts.CBS9106 is an inhibitor of CRM1-dependent nuclear export and reduces CRM1 protein levels.
Chemical Properties
| Molecular Formula | C18H21ClF3N3O3 |
| Molecular Weight | 419.83 |
| CAS Numbers | 1076235-04-5 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=C1C(=C(C(=O)N1NC2=NC(Cl)=C(C=C2)C(F)(F)F)COCCC(C)(C)C)C |
Storage and Handling
0C Short Term, -20C Long Term
References
Saito N,et al. CBS9106-induced CRM1 degradation is mediated by cullin ring ligase activity and the neddylation pathway. Mol Cancer Ther. 2014 Dec;13[12] 3013-23.