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Overview
Specific and potent inhibitor of V8 protease; Irreversible inhibitor of Staphylococcus aureus endoproteinase GluC
Chemical Properties
| Molecular Formula | C10H13N5O5 |
| Molecular Weight | 283.2 |
| CAS Numbers | 38819-10-2 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 2-amino-9-β-D-arabinofuranosyl-1,9-dihydro-6H-purin-6-one |
| InChl Key | NYHBQMYGNKIUIF-FJFJXFQQSA-N |
| InChl Code | InChI=1S/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6+,9-/m1/s1 |
| SMILES Code | O[C@H]1[C@H](O)[C@H](N2C=NC3=C2NC(N)=NC3=O)O[C@@H]1CO |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
Guanine Arabinoside; NSC 76352
References
1) Leanza, L., Miazzi, C., Ferraro, P., et al. Activation of guanine-β-D-arabinofuranoside and deoxyguanosine to triphosphates by a common pathway blocks T lymphoblasts at different checkpoints. Exp. Cell Res. 316(20), 3443-3453 (2010).