Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Cyclo(-RGDfK)
AOB0637
CAS 161552-03-0
Chemical Name: 2-[(2S,5R,8S,11S)-8-(4-Aminobutyl)-5-benzyl-11-[3-(diaminomethylideneamino)propyl]-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acid bis-TFA salt
1000 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $18.27 | Total: $91.37 |
| 1 | 10 | $15.48 | Total: $154.80 |
| 1 | 25 | $13.12 | Total: $327.88 |
| 1 | 50 | $11.18 | Total: $559.00 |
| 1 | 100 | $9.68 | Total: $967.50 |
Overview
Potent and selective avß3 integrin inhibitor
Chemical Properties
| Molecular Formula | C31H43F6N9O11 |
| Molecular Weight | 831.73 |
| CAS Numbers | 161552-03-0 (free base) |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 2-[(2S,5R,8S,11S)-8-(4-Aminobutyl)-5-benzyl-11-[3-(diaminomethylideneamino)propyl]-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acid bis-TFA salt |
| InChl Key | NVHPXYIRNJFKTE-HAGHYFMRSA-N |
| InChl Code | InChI=1S/C27H41N9O7/c28-11-5-4-9-18-24(41)34-17(10-6-12-31-27(29)30)23(40)32-15-21(37)33-20(14-22(38)39)26(43)36-19(25(42)35-18)13-16-7-2-1-3-8-16/h1-3,7-8,17-20H,4-6,9-15,28H2,(H,32,40)(H,33,37)(H,34,41)(H,35,42)(H,36,43)(H,38,39)(H4,29,30,31)/t17-,18-,19+,20-/m0/s1 |
| SMILES Code | NC(NCCC[C@@H](C(NCC(N[C@H]1CC(O)=O)=O)=O)NC([C@H](CCCCN)NC([C@@H](CC2=CC=CC=C2)NC1=O)=O)=O)=N |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
References
1) Šimeček, J., Notni, J., Kapp, T.G., et al. Benefits of NOPO as chelator in gallium-68 peptides, exemplified by preclinical characterization of 68Ga-NOPO-c(RGDfK). Mol. Pharm. 11(5), 1687-1695 (2014).
2) Dijkgraaf, I., Beer, A.J., and Wester, H.-J. Application of RGD-containing peptides as imaging probes for alphavbeta3 expression. Front. Biosci. (Landmark Ed.) 14(3), 887-899 (2009).