Fludrocortisone Acetate

Fludrocortisone Acetate

AOB0818

CAS 514-36-3

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Overview

Glucocorticoid-receptor and mineralocorticoid-receptor agonist, binding to cytoplasmic receptors, translocating to the nucleus, and subsequently initiating the transcription of glucocorticoid-responsive genes, stimulating Na reabsorption and water retention and K and H secretion in the distal tubules and collecting ducts of the kidney.