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Ionomycin Calcium Salt
AOB9252
CAS 56092-82-1
Chemical Name: Calcium (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-19,21-Dihydroxy-22-[(2S,5S)-5-[(2R,5S)-5-[(1R)-1-hydroxyethyl]-5-methyloxolan-2-yl]-5-methyloxolan-2-yl]-4,6,8,12,14,18,20-heptamethyl-11-oxido-9-oxodocosa-10,16-dienoate
1000 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $225.25 | Total: $1,126.25 |
| 1 | 10 | $190.80 | Total: $1,908.00 |
| 1 | 25 | $161.65 | Total: $4,041.25 |
| 1 | 50 | $137.80 | Total: $6,890.00 |
| 1 | 100 | $119.25 | Total: $11,925.00 |
Overview
Ca ionophore that is more effective than A23187 as a mobile ion carrier for Ca
Chemical Properties
| Molecular Formula | C41H70O9.Ca |
| Molecular Weight | 747.08 |
| CAS Numbers | 56092-82-1 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-Trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2'R,5S,5'S)-octahydro-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyl[2,2'-bifuran]-5-yl]-9-oxo-10,16-docosadienoic acid calcium salt |
| InChl Key | WKRWUYKLUMMAKG-WYGBAUISSA-L |
| SMILES Code | O=C([O-])CC[C@@H](C)C[C@H](C)C[C@H](C)C(/C=C([O-])/[C@H](C)C[C@@H](C/C=C/[C@@H](C)[C@@H](O)[C@@H](C)[C@@H](O)C[C@@H]1CC[C@]([C@]2([H])O[C@@]([C@H](O)C)(C)CC2)(C)O1)C)=O.[Ca+2] |
| PubChem ID | 6446270 |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
References
1) Elzi et al (2001) Ionomycin causes activation of p38 and p42/44 mitogen-activated protein kinases in human neutrophils. Am.J.Physiol.Cell Physiol. 281 C350 PMID: 11401859
2) Kaufmann et al (1980) Cation transport and specificity of ionomycin. Comparison with ionophore A23187 in rat liver mitochondria. J.Biol.Chem. 255 2735 PMID: 6766939