As2677131

As2677131

AOB9633

CAS 2171502-44-4

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1000 Items

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Overview

Novel and potent inhibitor of IL-12p40, a subunit of IL-23, exhibiting unique pharmacological activities in their inhibition of the production of IL-12p40, IL-6 and IL-1ß but not TNFalpha in activated macrophages or dendritic cells, and expression of IgM-induced MHC class II on B cells