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Levcromakalim
AOB9866
CAS 94535-50-9
Chemical Name: Lemakalim; (-)-Cromakalim; Cromakalim; BRL-38227; (3S,4R)-3-Hydroxy-2,2-dimethyl-4-(2-oxopyrrolidin-1-yl)-3,4-dihydrochromene-6-carbonitrile
1000 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $41.65 | Total: $208.25 |
| 1 | 10 | $35.28 | Total: $352.80 |
| 1 | 25 | $29.89 | Total: $747.25 |
| 1 | 50 | $25.48 | Total: $1,274.00 |
| 1 | 100 | $22.05 | Total: $2,205.00 |
Overview
Potassium-channel opening vasodilator
Chemical Properties
| Molecular Formula | C16H18N2O3 |
| Molecular Weight | 286.33 |
| CAS Numbers | 94535-50-9 |
| Solubility | DMSO : ≥ 50 mg/mL;H2O : < 0.1 mg/mL |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | (3S,4R)-3-Hydroxy-2,2-dimethyl-4-(2-oxopyrrolidin-1-yl)-3,4-dihydrochromene-6-carbonitrile |
| SMILES Code | CC(O1)(C)[C@@H](O)[C@H](N2CCCC2=O)C3=C1C=CC(C#N)=C3 |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
Lemakalim; (-)-Cromakalim; Cromakalim; BRL-38227;
References
1) Matsumoto T, et al. Tunicamycin-Induced Alterations in the Vasorelaxant Response in Organ-Cultured Superior Mesenteric Arteries of Rats. Biol Pharm Bull. 2016;39(9):1475-81.
2) Hong SH, et al. Regulation of myometrial contraction by ATP-sensitive potassium (KATP) channel via activation of SUR2B and Kir 6.2 in mouse. J Vet Med Sci. 2016 Aug 1;78(7):1153-9.