Brd4592

Brd4592

AOB37291

CAS 2109805-80-1

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Overview

Novel allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase (TrpAB), bindomg at the TrpAB α-β-subunit interface and affecting multiple steps in the enzyme's overall reaction, resulting in inhibition not easily overcome by changes in metabolic environment.