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AMD3100 Octahydrochloride Bulk
AOB33719B
CAS 155148-31-5
Chemical Name: Plerixafor; Mozobil; 1-[[4-(1,4,8,11-Tetrazacyclotetradec-1-ylmethyl)phenyl]methyl]-1,4,8,11-tetrazacyclotetradecane octahydrochloride
1000 Items
Overview
Chemokine receptor CXCR4 antagonist
Chemical Properties
| Molecular Formula | C28H62Cl8N8 |
| Molecular Weight | 794.47 |
| CAS Numbers | 155148-31-5 |
| Solubility | DMSO and Water |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 1-[[4-(1,4,8,11-Tetrazacyclotetradec-1-ylmethyl)phenyl]methyl]-1,4,8,11-tetrazacyclotetradecane octahydrochloride |
| InChl Key | UEUPDYPUTTUXLJ-UHFFFAOYSA-N |
| SMILES Code | C1(CN3CCCNCCNCCCNCC3)=CC=C(CN2CCCNCCNCCCNCC2)C=C1.Cl.Cl.Cl.Cl.Cl.Cl.Cl.Cl |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
Plerixafor; Mozobil
References
1) Bridger et al (1995) Synthesis and structure-activity relationships of phenylenebis(methylene)-linked bis-tetraazamacrocycles that inhibits HIV replication. Effects of macrocyclic ring size and substituents on the aromatic linker. J.Med.Chem. 38 366 PMID: 7830280
2) Hogaboam et al (2005) The therapeutic potential in targeting CCR5 and CXCR4 receptors in infectious and allergic pulmonary disease. Pharmacol.Ther. 107 314 PMID: 16009428