Chebulinic Acid

Chebulinic Acid

AOB33628

CAS 18942-26-2

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Overview

Potent protectant against glutamate-induced neuronal cell death, significantly reducing intracellular reactive oxygen species (ROS) production and Ca2+ influx induced by glutamate, decreasing the phosphorylation of mitogen-activated protein kinases (MAPKs), including ERK1/2, JNK, and p38, as well as inhibiting pro-apoptotic Bax and increasing anti-apoptotic Bcl-2 protein expression