Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Aflatoxin B1
AOB17687
CAS 1162-65-8
Chemical Name: AFB1; (6aR,9aS)-4-Methoxy-2,3,6a,9a-tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene-1,11-dione
980 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $68.85 | Total: $344.25 |
| 1 | 10 | $58.32 | Total: $583.20 |
| 1 | 25 | $49.41 | Total: $1,235.25 |
| 1 | 50 | $42.12 | Total: $2,106.00 |
| 1 | 100 | $36.45 | Total: $3,645.00 |
Overview
Natural potent hepatotoxic and hepatocarcinogenic mycotoxin, being also mutagenic, teratogenic, and causing immunosuppression in animals
Chemical Properties
| Molecular Formula | C17H12O6 |
| Molecular Weight | 312.3 |
| CAS Numbers | 1162-65-8 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 2,3,6aR,9aS-tetrahydro-4-methoxy-1H,11H-cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione |
| InChl Key | OQIQSTLJSLGHID-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C17H12O6/c1-20-10-6-11-14(8-4-5-21-17(8)22-11)15-13(10)7-2-3-9(18)12(7)16(19)23-15/h4-6,8,17H,2-3H2,1H3 |
| SMILES Code | O=C1C2=C(CCC2=O)C3=C(C(C(C=CO4)C4O5)=C5C=C3OC)O1 |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
AFB1; HSDB 3453; NSC 529592
References
1) Essigmann, J.M., Croy, R.G., Nadzan, A.M., et al. Structural identification of the major DNA adduct formed by aflatoxin B1 in vitro. Proc. Natl. Acad. Sci. USA 74(5), 1870-1874 (1977).
2) Aguilar, F., Hussain, S.P., and Cerutti, P. Aflatoxin B1 induces the transversion of G -> T in codon 249 of the p53 tumor suppressor gene in human hepatocytes. Proc. Natl. Acad. Sci. USA 90(18), 8586-8590 (1993).