Pf-04449613

Pf-04449613

AOB13513

CAS 1236858-52-8

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Overview

Novel potent and selective, orally active pantothenate kinase (PANK) modulator, acting as an orthosteric inhibitor (IC50=1.3 nM, hPANK3) and an allosteric activator of PANK3 activity in the presence of acetyl-CoA