Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
HHS-475
AOB13969
CAS N/A
Chemical Name: 4-((1H-1,2,4-Triazol-1-yl)sulfonyl)-N-(prop-2-yn-1-yl)benzamide
1000 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $84.15 | Total: $420.75 |
| 1 | 10 | $71.28 | Total: $712.80 |
| 1 | 25 | $60.39 | Total: $1,509.75 |
| 1 | 50 | $51.48 | Total: $2,574.00 |
| 1 | 100 | $44.55 | Total: $4,455.00 |
Overview
Novel sulfur-triazole exchange (SuTEx) covalent probe with ~5-fold enhanced chemoselectivity for tyrosines over other nucleophilic amino acids
Chemical Properties
| Molecular Formula | C12H10N4O3S |
| Molecular Weight | 290.297 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 4-((1H-1,2,4-Triazol-1-yl)sulfonyl)-N-(prop-2-yn-1-yl)benzamide |
| InChl Key | ZBNCPAXYEUCPRL-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C12H10N4O3S/c1-2-7-14-12(17)10-3-5-11(6-4-10)20(18,19)16-9-13-8-15-16/h1,3-6,8-9H,7H2,(H,14,17) |
| SMILES Code | O=C(NCC#C)C1=CC=C(S(=O)(N2N=CN=C2)=O)C=C1 |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
HHS-475; HHS 475; HHS475
References
1) Heung Sik Hahm et al., Global targeting of functional tyrosines using sulfur-triazole exchange chemistry, Nature Chemical Biology volume 16, pages150–159 (2020)