Tcmdc-135051 Tfa Salt

Tcmdc-135051 Tfa Salt

AOB11042

CAS 2413716-15-9

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Overview

Novel Inhibitor of the malaria parasite protein kinase CLK3, inhibiting the development of liver-stage parasites, killing asexual blood-stage parasites at the trophozoite and schizont stages of the erythrocytic cycle, blocking the development of sexual gametocytes that infect mosquitoes, and blocks exflagellation that results in male gametes