Nfat:ap-1 Inhibitor-10

Nfat:ap-1 Inhibitor-10

AOB14687

CAS 841210-82-0

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Overview

Novel inhibitor of the NFAT:AP-1:DNA interaction on the ARRE-2 element, binding to DNA in a sequence-selective manner and inhibiting the transcription of the Il2 gene and several other cyclosporin A-sensitive cytokine genes important for the effector immune response