Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $132.60 | Total: $663.00 |
| 1 | 10 | $112.32 | Total: $1,123.20 |
| 1 | 25 | $95.16 | Total: $2,379.00 |
| 1 | 50 | $81.12 | Total: $4,056.00 |
| 1 | 100 | $70.20 | Total: $7,020.00 |
Overview
(Rac)-AMXT-1501 4HCl is a polyamine transport inhibitor that inhibits polyamine transport and acts synergistically with cisplatin in HNSCC. (Rac)-AMXT-1501 4HCl has potential antimicrobial activity and inhibits neuroblastoma cell proliferation and pneumococcal pod biosynthesis by targeting ornithine decarboxylase and polyamine transport.
Chemical Properties
| Molecular Formula | C32H72Cl4N6O2 |
| Molecular Weight | 714.77 |
| CAS Numbers | 2771343-93-0 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=C(CCCCCCCCCCCCCCC)NCCCCC(C(NCCCNCCCCNCCCN)=O)N.Cl.Cl.Cl.Cl |
Storage and Handling
0C Short Term, -20C Long Term
References
Hayes CS, et al. Polyamine-blocking therapy reverses immunosuppression in the tumor microenvironment. Cancer Immunol Res. 2014 Mar;2[3] 274-85.