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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $253.30 | Total: $1,266.50 |
| 1 | 10 | $214.56 | Total: $2,145.60 |
| 1 | 25 | $181.78 | Total: $4,544.50 |
| 1 | 50 | $154.96 | Total: $7,748.00 |
| 1 | 100 | $134.10 | Total: $13,410.01 |
Overview
Talotrexin ammonium is a non-polyglutamic acid antifolate. Talotrexin ammonium inhibits tumor growth by targeting dihydrofolate reductase (DHFR), thereby improving anti-tumor activity in a wide range of cancer models, helping to inhibit tumor growth.
Chemical Properties
| Molecular Formula | C27H30N10O6 |
| Molecular Weight | 590.59 |
| CAS Numbers | 648420-92-2 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | NC=1C2=C(N=CC(CNC3=CC=C(C(N[C@@H](CCCNC(=O)C4=C(C(O)=O)C=CC=C4)C(O)=O)=O)C=C3)=N2)N=C(N)N1.N |
Storage and Handling
0C Short Term, -20C Long Term
References
C S Rocha Lima, et al. A phase I study of talotrexin [PT-523] in patients with relapsed or refractory non-small cell lung cancer [NSCLC].