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JNJ-56022486
AOB31959
CAS: 2036082-79-6
Chemical Name: 2-(3-Chloro-2-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)phenyl)acetonitrile
1000 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $31.87 | Total: $159.37 |
| 1 | 10 | $27.00 | Total: $270.00 |
| 1 | 25 | $22.88 | Total: $571.88 |
| 1 | 50 | $19.50 | Total: $975.00 |
| 1 | 100 | $16.88 | Total: $1,687.50 |
Overview
A novel potent and selective negative modulator of AMPA receptors containing TARP-gamma8
Chemical Properties
| Molecular Formula | C15H10ClN3O |
| Molecular Weight | 283.72 |
| CAS Numbers | 2036082-79-6 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 2-(3-chloro-2-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)phenyl)acetonitrile |
| InChl Key | WJCNWFPRVRWFCU-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C15H10ClN3O/c16-11-3-1-2-9(6-7-17)14(11)10-4-5-12-13(8-10)19-15(20)18-12/h1-5,8H,6H2,(H2,18,19,20) |
| SMILES Code | N#CCC1=CC=CC(Cl)=C1C2=CC=C(C(N3)=C2)NC3=O |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
JNJ-56022486; JNJ 56022486; JNJ56022486
References
1) Maher MP, Ameriks MK, Savall BM, Carruthers NI, Lovenberg TW. Reply to "A Comment on 'Discovery and Characterization of AMPA Receptor Modulators Selective for TARP-γ8'". J Pharmacol Exp Ther. 2016 Sep;358(3):527.
2) Witkin JM, Gardinier KM. A Comment on "Discovery and Characterization of AMPA Receptor Modulators Selective for TARP-γ8". J Pharmacol Exp Ther. 2016 Sep;358(3):502-3.