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CDPPB
AOB1083
CAS: 781652-57-1
Chemical Name: 3-Cyano-N-1,3-diphenyl-1H-pyrazol-5-yl)benzamide
950 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $12.75 | Total: $63.75 |
| 1 | 10 | $10.80 | Total: $108.00 |
| 1 | 25 | $9.15 | Total: $228.75 |
| 1 | 50 | $7.80 | Total: $390.00 |
| 1 | 100 | $6.75 | Total: $675.00 |
Overview
Glutamate metabotropic mGluR5 positive allosteric modulator
Chemical Properties
| Molecular Formula | C23H16N4O |
| Molecular Weight | 364.4 |
| CAS Numbers | 781652-57-1 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide Purity: ≥98% (HPLC) |
| InChl Key | BKUIZWILNWHFHD-UHFFFAOYSA-N |
| SMILES Code | O=C(C4=CC(C#N)=CC=C4)NC1=CC(C3=CC=CC=C3)=NN1C2=CC=CC=C2 |
| PubChem ID | 11245456 |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
References
1) Lindsley et al (2004) Discovery of positive allosteric modulators for the metabotropic glutamate receptor subtype 5 from a series of N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamides that potentiate receptor function in vivo. J.Med.Chem. 47 5825 PMID: 15537338
2) Kinney et al (2005) A novel selective positive allosteric modulator of metabotropic glutamate receptor subtype 5 has in vivo activity and antipsychotic-like effects in rats behavioral models. J.Pharmacol.Exp.Ther. 313 199 PMID: 15608073