Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $124.95 | Total: $624.75 |
| 1 | 10 | $105.84 | Total: $1,058.40 |
| 1 | 25 | $89.67 | Total: $2,241.75 |
| 1 | 50 | $76.44 | Total: $3,822.00 |
| 1 | 100 | $66.15 | Total: $6,615.00 |
Overview
CBiPES hydrochloride (CBiPES HCl) is a potent orthosteric modulator of the mGlu2 receptor with an EC50 value of 92.8 nM.CBiPES hydrochloride blocks the action of WT and mGlu(3) receptors.CBiPES hydrochloride can be used to study neurological disorders like epilepsy and Parkinson's syndrome. CBiPES hydrochloride can be used to study neurological disorders like epilepsy and Parkinson's syndrome.
Chemical Properties
| Molecular Formula | C21H20ClN3O2S |
| Molecular Weight | 413.92 |
| CAS Numbers | 856702-40-4 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cl.N#CC1=CC=C(C=C1)C=2C=CC=C(C2)N(CC=3C=NC=CC3)S(=O)(=O)CC |
Storage and Handling
0C Short Term, -20C Long Term
References
Frouni I, et al. Effect of the mGlu2 positive allosteric modulator CBiPES on dyskinesia, psychosis-like behaviours and parkinsonism in the MPTP-lesioned marmoset. J Neural Transm [Vienna]. 2021 Jan;128[1] 73-81.