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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $22.10 | Total: $110.50 |
| 1 | 10 | $18.72 | Total: $187.20 |
| 1 | 25 | $15.86 | Total: $396.50 |
| 1 | 50 | $13.52 | Total: $676.00 |
| 1 | 100 | $11.70 | Total: $1,170.00 |
Overview
ML337 is a negative allosteric modulator of mGlu3 with an IC50 of 593 nM.
Chemical Properties
| Molecular Formula | C21H20FNO3 |
| Molecular Weight | 353.39 |
| CAS Numbers | 1443118-44-2 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | COc1ccc(cc1)C#Cc1ccc(C(=O)N2CCC[C@@H](O)C2)c(F)c1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Wenthur CJ, et, al. Discovery of [R]-[2-fluoro-4-[[-4-methoxyphenyl]ethynyl]phenyl] [3-hydroxypiperidin-1-yl]methanone [ML337], an mGlu3 selective and CNS penetrant negative allosteric modulator [NAM]. J Med Chem. 2013 Jun 27; 56[12] 5208-12.