Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $25.50 | Total: $127.50 |
| 1 | 10 | $21.60 | Total: $216.00 |
| 1 | 25 | $18.30 | Total: $457.50 |
| 1 | 50 | $15.60 | Total: $780.00 |
| 1 | 100 | $13.50 | Total: $1,350.00 |
Overview
SYM2206 is a low affinity non-competitive AMPA receptor antagonist with an IC50 value of 1.6 ?M.SYM2206 exhibits anticancer activity by blocking Nav1.6-mediated sustained currents and decreasing the survival of pancreatic cancer cells.
Chemical Properties
| Molecular Formula | C20H22N4O3 |
| Molecular Weight | 366.41 |
| CAS Numbers | 173952-44-8 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CCCNC(=O)N1N=C(c2ccc(N)cc2)c2cc3OCOc3cc2C1C |
Storage and Handling
0C Short Term, -20C Long Term
References
Welch NC, et al. Traditional AMPA receptor antagonists partially block Na v1.6-mediated persistent current. Neuropharmacology. 2008 Dec;55[7] 1165-71.