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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $30.60 | Total: $153.00 |
| 1 | 10 | $25.92 | Total: $259.20 |
| 1 | 25 | $21.96 | Total: $549.00 |
| 1 | 50 | $18.72 | Total: $936.00 |
| 1 | 100 | $16.20 | Total: $1,620.00 |
Overview
(R)-ADX-47273 is a potent positive allosteric modulator of mGluR5, with an EC50 of 168 nM for potentiation.
Chemical Properties
| Molecular Formula | C20H17F2N3O2 |
| Molecular Weight | 369.36 |
| CAS Numbers | 851881-59-9 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Fc1ccc(cc1)C(=O)N1CCC[C@H](C1)c1nc(no1)-c1ccc(F)cc1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Engers DW, et al. Synthesis, SAR and unanticipated pharmacological profiles of analogues of the mGluR5 ago-potentiator ADX-4727ChemMedChem. 2009 Apr;4[4] 505-11.