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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $34.85 | Total: $174.25 |
| 1 | 10 | $29.52 | Total: $295.20 |
| 1 | 25 | $25.01 | Total: $625.25 |
| 1 | 50 | $21.32 | Total: $1,066.00 |
| 1 | 100 | $18.45 | Total: $1,845.00 |
Overview
Fenobam shows inverse agonist activity which blocks the mGlu5 receptor basal activity(IC50: 84 nM). Fenobam has anxiolytic activity. Fenobam is a selective and non-competitive mGluR5 antagonist acting at an allosteric modulatory site (Kd values are 54 and 31 nM for rat and human recombinant mGlu5 receptors, respectively).
Chemical Properties
| Molecular Formula | C11H11ClN4O2 |
| Molecular Weight | 266.68 |
| CAS Numbers | 57653-26-6 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CN1CC(=O)N=C1NC(=O)Nc1cccc(Cl)c1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Porter RH, et al. Fenobam a clinically validated nonbenzodiazepine anxiolytic is a potent, selective, and noncompetitive mGlu5 receptor antagonist with inverse agonist activity. J Pharmacol Exp Ther. 2005 Nov;315[2] 711-21.