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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $22.10 | Total: $110.50 |
| 1 | 10 | $18.72 | Total: $187.20 |
| 1 | 25 | $15.86 | Total: $396.50 |
| 1 | 50 | $13.52 | Total: $676.00 |
| 1 | 100 | $11.70 | Total: $1,170.00 |
Overview
S 18986 is a selective, orally active, brain-penetrant positive allosteric modulator of AMPA-type receptors that enhances cognition in rodents by inducing the release of noradrenaline and acetylcholine in the rat hippocampus, subsequently improving object-recognition memory.
Chemical Properties
| Molecular Formula | C10H12N2O2S |
| Molecular Weight | 224.28 |
| CAS Numbers | 175340-20-2 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=S1(=O)C=2C(N3[C@@](N1)(CCC3)[H])=CC=CC2 |
Storage and Handling
0C Short Term, -20C Long Term
References
Bernard K, et al. DRUG FOCUS S 18986 A positive allosteric modulator of AMPA-type glutamate receptorspharmacological profile of a novel cognitive enhancer. CNS Neurosci Ther. 2010 Oct;16[5] e193-212.