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M77976
AOB33474
CAS No: 394237-61-7
Chemical Name: 4-[4-(4-Methoxy-phenyl)-5-methyl-1H-pyrazol-3-yl]-benzene-1,3-diol
1990 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $21.25 | Total: $106.25 |
| 1 | 10 | $18.00 | Total: $180.00 |
| 1 | 25 | $15.25 | Total: $381.25 |
| 1 | 50 | $13.00 | Total: $650.00 |
| 1 | 100 | $11.25 | Total: $1,125.00 |
Overview
Novel specific inhibitor of PDK4. binding to the ATP-binding pocket of PDK4 and causes local conformational changes with complete disordering of the ATP lid
Chemical Properties
| Molecular Formula | C17H16N2O3 |
| Molecular Weight | 296.33 |
| CAS Numbers | 394237-61-7 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 4-(4-(4-methoxyphenyl)-5-methyl-1H-pyrazol-3-yl)benzene-1,3-diol |
| InChl Key | GSBFARPNIZUMHA-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C17H16N2O3/c1-10-16(11-3-6-13(22-2)7-4-11)17(19-18-10)14-8-5-12(20)9-15(14)21/h3-9,20-21H,1-2H3,(H,18,19) |
| SMILES Code | COC1=CC=C(C2=C(C)NN=C2C3=CC=C(O)C=C3O)C=C1 |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
M77976; M-77976; M 77976.
References
Kukimoto-Niino M, Tokmakov A, Terada T, Ohbayashi N, Fujimoto T, Gomi S, Shiromizu I, Kawamoto M, Matsusue T, Shirouzu M, Yokoyama S. Inhibitor-bound structures of human pyruvate dehydrogenase kinase 4. Acta Crystallogr D Biol Crystallogr. 2011 Sep;67(Pt 9):763-73.