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JMS-053
AOB31947
CAS: 1954650-11-3
Chemical Name: JMS-631-053; 7-Imino-2-phenylthieno[3,2-c]pyridine-4,6(5H,7H)-dione
AOBIOUS launched this product in 2019
CITATIONS - Publications That Use AOBIOUS Product
2000 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $101.15 | Total: $505.75 |
| 1 | 10 | $85.68 | Total: $856.80 |
| 1 | 25 | $72.59 | Total: $1,814.75 |
| 1 | 50 | $61.88 | Total: $3,094.00 |
| 1 | 100 | $53.55 | Total: $5,355.00 |
Overview
Novel allosteric PTP4A3 inhibitor, increasing Emilin 1 gene expression
Chemical Properties
| Molecular Formula | C13H8N2O2S |
| Molecular Weight | 256.28 |
| CAS Numbers | 1954650-11-3 |
| Solubility | DMSO and Water |
| Purity | 99% (HPLC) |
| IUPAC/Chemical Name | 7-Imino-2-phenylthieno[3,2-c]pyridine-4,6(5H,7H)-dione |
| InChl Key | CQHAROORCYWRRH-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C13H8N2O2S/c14-10-11-8(12(16)15-13(10)17)6-9(18-11)7-4-2-1-3-5-7/h1-6,14H,(H,15,16,17) |
| SMILES Code | O=C1C(C=C(C2=CC=CC=C2)S3)=C3C(C(N1)=O)=N |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
JMS-631-053; JMS053; JMS 053; JMS-053
References
1) McQueeney KE etc. Targeting ovarian cancer and endothelium with an allosteric PTP4A3 phosphatase inhibitor, Oncotarget. 2017 Dec 30;9(9):8223-8240
2) Sharon R etc. The Mechanism of Inhibition of the Undrugged Oncogenic Phosphatase PTP4A3 by a Novel Small Molecule JMS-053, FASEB Journal Vol. 33, No. 1 April 2019
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