DO53

DO53

AOB8065

CAS: 1848233-59-9

 

Chemical Name: 3-Phenyl-4-[[4-[4-(trifluoromethoxy)phenyl]-1H-1,2,3-triazol-1-yl]carbonyl]-1-piperazinecarboxylic acid 1,1-dimethylethyl ester

More details

2000 Items

$48.75

$48.75 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $31.87 Total: $159.37
110 $27.00 Total: $270.00
125 $22.88 Total: $571.88
150 $19.50 Total: $975.00
1100 $16.88 Total: $1,687.50

Overview

Negative control for DO34, not inhibiting DAGL






























Chemical Properties

Molecular FormulaC25H26F3N5O4
Molecular Weight517.51
CAS Numbers1848233-59-9
SolubilityDMSO
Purity98% by HPLC
IUPAC/Chemical Name3-Phenyl-4-[[4-[4-(trifluoromethoxy)phenyl]-1H-1,2,3-triazol-1-yl]carbonyl]-1-piperazinecarboxylic acid 1,1-dimethylethyl ester
InChl KeyMCQNBNJCBIKELG-UHFFFAOYSA-N
InChl CodeInChI=1S/C25H26F3N5O4/c1-24(2,3)37-23(35)31-13-14-32(21(16-31)18-7-5-4-6-8-18)22(34)33-15-20(29-30-33)17-9-11-19(12-10-17)36-25(26,27)28/h4-12,15,21H,13-14,16H2,1-3H3
SMILES CodeO=C(N1CC(C2=CC=CC=C2)N(C(N3N=NC(C4=CC=C(OC(F)(F)F)C=C4)=C3)=O)CC1)OC(C)(C)C

Storage and Handling

0°C (short term), -20°C (long term), desiccated

References

1) Deng H, Kooijman S, van den Nieuwendijk AM, Ogasawara D, van der Wel T, van Dalen F, Baggelaar MP, Janssen FJ, van den Berg RJ, den Dulk H, Cravatt BF, Overkleeft HS, Rensen PC, van der Stelt M. Triazole Ureas Act as Diacylglycerol Lipase Inhibitors and Prevent Fasting-Induced Refeeding. J Med Chem. 2017 Jan 12;60(1):428-440. doi: 10.1021/acs.jmedchem.6b01482. Epub 2016 Dec 19. PubMed PMID: 27992221.

2) Witter K, Matulová P, Mísek I. Three-dimensional reconstruction studies and morphometric analysis of rudimental tooth primordia in the upper incisor region of the sheep (Ovis aries, Ruminantia). Arch Oral Biol. 2003 Jan;48(1):15-24. PubMed PMID: 12615137.