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VT-104
AOB12135
CAS: 2417718-25-1
Chemical Name: (S)-N-(1-(Pyridin-2-yl)ethyl)-5-(4-(trifluoromethyl)phenyl)-2-naphthamide
1811 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity (mg or Unit) | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|
| 5 | $50.15 | Total: $250.75 |
| 10 | $42.48 | Total: $424.80 |
| 25 | $35.99 | Total: $899.75 |
| 50 | $30.68 | Total: $1,534.00 |
| 100 | $26.55 | Total: $2,655.00 |
Overview
Novel potent and selective TEAD Auto-palmitoylation inhibitor
Chemical Properties
| Molecular Formula | C25H19F3N2O |
| Molecular Weight | 420.44 |
| CAS Numbers | 2417718-25-1 (S-isomer) |
| Solubility | DMSO and Alcohol |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | (S)-N-(1-(pyridin-2-yl)ethyl)-5-(4-(trifluoromethyl)phenyl)-2-naphthamide |
| InChl Key | AAZUPSFRSHFTGV-INIZCTEOSA-N |
| InChl Code | InChI=1S/C25H19F3N2O/c1-16(23-7-2-3-14-29-23)30-24(31)19-10-13-22-18(15-19)5-4-6-21(22)17-8-11-20(12-9-17)25(26,27)28/h2-16H,1H3,(H,30,31)/t16-/m0/s1 |
| SMILES Code | FC(F)(F)C(C=C1)=CC=C1C2=CC=CC3=CC(C(N[C@@H](C)C4=NC=CC=C4)=O)=CC=C23 |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
VT-104; VT 104; VT104
References
1) Tang TT, Konradi AW, Feng Y, Peng X, Ma M, Li J, Yu FX, Guan KL, Post L. Small Molecule Inhibitors of TEAD Auto-palmitoylation Selectively Inhibit Proliferation and Tumor Growth of NF2-deficient Mesothelioma. Mol Cancer Ther. 2021 Apr 13:molcanther.0717.2020. doi: 10.1158/1535-7163.MCT-20-0717. Epub ahead of print. PMID: 33850002.
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