ERDRP-0519

ERDRP-0519

AOB2063

CAS No: 1374006-96-8

Chemical Name: 1-Methyl-N-[4-[[(2S)-2-[2-(4-morpholinyl)ethyl]-1-piperidinyl]sulfonyl]phenyl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide

AOBIOUS launched this product in 2015

CITATIONS - Publications That Use AOBIOUS Product

1) BMC Veterinary Research, 25 Jan 2022, 18(1):55

2) Nature Communications, 13 Oct 2025, 16(1):9061

More details

266 Items

$69.00

$69.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $58.65 Total: $293.25
110 $49.68 Total: $496.80
125 $42.09 Total: $1,052.25
150 $35.88 Total: $1,794.00
1100 $31.05 Total: $3,105.00

Overview

Novel Orally Available Polymerase Inhibitor, Showing Efficacy Against a Lethal Morbillivirus Infection in a Large Animal Model

Chemical Properties

Molecular FormulaC23H30F3N5O4S
Molecular Weight529.58
CAS Numbers1374006-96-8
SolubilityDMSO
Purity98% by HPLC
IUPAC/Chemical Name1-Methyl-N-[4-[[(2S)-2-[2-(4-morpholinyl)ethyl]-1-piperidinyl]sulfonyl]phenyl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
InChl Key JVZHTUQIMBYDSX-SFHVURJKSA-N
InChl CodeInChI=1S/C23H30F3N5O4S/c1-29-20(16-21(28-29)23(24,25)26)22(32)27-17-5-7-19(8-6-17)36(33,34)31-10-3-2-4-18(31)9-11-30-12-14-35-15-13-30/h5-8,16,18H,2-4,9-15H2,1H3,(H,27,32)/t18-/m0/s1
SMILES CodeO=C(C1=CC(C(F)(F)F)=NN1C)NC2=CC=C(S(=O)(N3[C@H](CCN4CCOCC4)CCCC3)=O)C=C2

Storage and Handling

0°C (short term), -20°C (long term), desiccated

Synonyms

ERDRP-0519; ERDRP 0519; ERDRP0519;

References

1) Krumm SA, Yan D, Hovingh ES, Evers TJ, Enkirch T, Reddy GP, Sun A, Saindane MT, Arrendale RF, Painter G, Liotta DC, Natchus MG, von Messling V, Plemper RK. An orally available, small-molecule polymerase inhibitor shows efficacy against a lethal morbillivirus infection in a large animal model. Sci Transl Med. 2014 Apr 16;6(232):232ra52. doi: 10.1126/scitranslmed.3008517. PubMed PMID: 24739760; PubMed Central PMCID: PMC4080709.

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