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PF-04457845
AOB9007
CAS: 1020315-31-4
Chemical Name: N-Pyridazin-3-yl-4-[[3-[5-(trifluoromethyl)pyridin-2-yl]oxyphenyl]methylidene]piperidine-1-carboxamide
993 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $12.75 | Total: $63.75 |
| 1 | 10 | $10.80 | Total: $108.00 |
| 1 | 25 | $9.15 | Total: $228.75 |
| 1 | 50 | $7.80 | Total: $390.00 |
| 1 | 100 | $6.75 | Total: $675.00 |
Overview
Potent, orally active, irreversible inhibitor of fatty acid amide hydrolase (FAAH)
Chemical Properties
| Molecular Formula | C23H20F3N5O2 |
| Molecular Weight | 455.43 |
| CAS Numbers | 1020315-31-4 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | N-3-pyridazinyl-4-[[3-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]methylene]-1-piperidinecarboxamide |
| InChl Key | BATCTBJIJJEPHM-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C23H20F3N5O2/c24-23(25,26)18-6-7-21(27-15-18)33-19-4-1-3-17(14-19)13-16-8-11-31(12-9-16)22(32)29-20-5-2-10-28-30-20/h1-7,10,13-15H,8-9,11-12H2,(H,29,30,32) |
| SMILES Code | O=C(NC1=CC=CN=N1)N(CC/2)CCC2=CC3=CC=CC(OC4=CC=C(C(F)(F)F)C=N4)=C3 |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
References
Johnson, D.S., Stiff, C., Lazerwith, S.E., et al. Discovery of PF-04457845: A highly potent, orally bioavailable, and selective urea FAAH inhibitor. ACS Med.Chem.Lett. 2(2), 91-96 (2011).