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NecroX-5
AOB9963
CAS 1383718-29-3
Chemical Name: 5-[(1,1-Dioxido-4-thiomorpholinyl)methyl]-2-phenyl-N-[(tetrahydro-2H-pyran-4-yl)methyl]-1H-indol-7-amine dimesylate
1000 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $26.35 | Total: $131.75 |
| 1 | 10 | $22.32 | Total: $223.20 |
| 1 | 25 | $18.91 | Total: $472.75 |
| 1 | 50 | $16.12 | Total: $806.00 |
| 1 | 100 | $13.95 | Total: $1,395.00 |
Overview
Novel mitochondrial ROS inhibitor
Chemical Properties
| Molecular Formula | C25H31N3O3S • 2CH4O3S |
| Molecular Weight | 645.8 |
| CAS Numbers | 1383718-29-3 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 5-[(1,1-dioxido-4-thiomorpholinyl)methyl]-2-phenyl-N-[(tetrahydro-2H-pyran-4-yl)methyl]-1H-indol-7-amine, dimethanesulfonate |
| InChl Key | ZWWWDIWEZYRVMB-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C25H31N3O3S.2CH4O3S/c29-32(30)12-8-28(9-13-32)18-20-14-22-16-23(21-4-2-1-3-5-21)27-25(22)24(15-20)26-17-19-6-10-31-11-7-19;2*1-5(2,3)4/h1-5,14-16,19,26-27H,6-13,17-18H2;2*1H3,(H,2,3,4) |
| SMILES Code | O=S(CCN1CC2=CC(NCC3CCOCC3)=C(NC(C4=CC=CC=C4)=C5)C5=C2)(CC1)=O.OS(C)(=O)=O.OS(C)(=O)=O |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
Necrosis Inhibitor 5, Necrox-5
References
1) Kim, H.J., Koo, S.Y., Ahn, B.H., et al. NecroX as a novel class of mitochondrial reactive oxygen species and ONOO- scavenger. Arch. Pharm. Res. 33(11), 1813-1823 (2010).