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SR-18292
AOB37750
CAS No: 2095432-55-4
Chemical Name: 1-[tert-Butyl-(4-methyl-benzyl)-amino]-3-(1H-indol-4-yloxy)-propan-2-ol
359 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $12.75 | Total: $63.75 |
| 1 | 10 | $10.80 | Total: $108.00 |
| 1 | 25 | $9.15 | Total: $228.75 |
| 1 | 50 | $7.80 | Total: $390.00 |
| 1 | 100 | $6.75 | Total: $675.00 |
Overview
Novel Selective Inhibitor of PGC-1alpha Gluconeogenic Activity, Ameliorating Type 2 Diabetes.
Reference:
Sharabi K, Lin H, Tavares CD, Dominy JE, Camporez JP, Perry RJ, Schilling R, Rines AK, Lee J, Hickey M, Bennion M, Palmer M, Nag PP, Bittker JA, Perez J, Jedrychowski MP, Ozcan U, Gygi SP, Kamenecka TM, Shulman GI, Schreiber SL, Griffin PR, Puigserver P. Selective Chemical Inhibition of PGC-1α Gluconeogenic Activity Ameliorates Type 2 Diabetes. Cell. 2017 Mar 23;169(1):148-160.e15. doi: 10.1016/j.cell.2017.03.001. PubMed PMID: 28340340.
Chemical Properties
| Molecular Formula | C23H30N2O2 |
| Molecular Weight | 366.51 |
| CAS Numbers | 2095432-55-4 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 1-[(1,1-dimethylethyl)[(4-methylphenyl)methyl]amino]-3-(1H-indol-4-yloxy)-2-propanol |
| InChl Key | BNRANURXPKRRKP-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C23H30N2O2/c1-17-8-10-18(11-9-17)14-25(23(2,3)4)15-19(26)16-27-22-7-5-6-21-20(22)12-13-24-21/h5-13,19,24,26H,14-16H2,1-4H3 |
| SMILES Code | CC(C)(C)N(CC(O)COC1=CC=CC2=C1C=CN2)CC3=CC=C(C)C=C3 |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
SR-18292; SR 18292; SR18292
References
1) Sharabi, K., et al. Selective chemical inhibition of PGC-1α gluconeogenic activity ameliorates Type 2 Diabetes. Cell 169(1), 148-160 (2017).
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