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Overview
Sodium etidronate (Didronel) is a synthetic therapeutic diphosphonate analog of endogenous pyrophosphate. As a member of the family of drugs known as bisphosphonates, Sodium etidronate differs from endogenous pyrophosphate in its resistance to enzymatic hydrolysis. This agent adsorbs to hydroxyapatite cells and reduces the number of osteoclasts, thereby inhibiting abnormal bone resorption. Etidronate may also directly stimulate bone formation by osteoblasts.
Chemical Properties
| Molecular Formula | C2H6Na2O7P2 |
| Molecular Weight | 249.99 |
| CAS Numbers | 7414-83-7 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | |
| InChl Key | |
| InChl Code | |
| SMILES Code | [Na+].[Na+].CC(O)(P(O)([O-])=O)P(O)([O-])=O |
Storage and Handling
0C Short Term, -20C Long Term
Synonyms
References
Grases F, et al. Circ J. 2007 Jul; 71[7] 1152-6.