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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $37.40 | Total: $187.00 |
| 1 | 10 | $31.68 | Total: $316.80 |
| 1 | 25 | $26.84 | Total: $671.00 |
| 1 | 50 | $22.88 | Total: $1,144.00 |
| 1 | 100 | $19.80 | Total: $1,980.00 |
Overview
BCI ((E)-BCI) is an allosteric inhibitor of dual-specificity phosphatases (DUSP), with EC50 values of 13.3 ?M for DUSP6 and 8.0 ?M for DUSP1 in cells, and does not inhibit DUSP5.
Chemical Properties
| Molecular Formula | C22H23NO |
| Molecular Weight | 317.42 |
| CAS Numbers | 1245792-51-1 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=C1C(=Cc2ccccc2)C(NC2CCCCC2)c2ccccc12 |
Storage and Handling
0C Short Term, -20C Long Term
References
Korotchenko VN, et al. In vivo structure-activity relationship studies support allosteric targeting of a dual specificity phosphatase. Chembiochem. 2014 Jul 7;15[10] 1436-45.