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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $215.05 | Total: $1,075.25 |
| 1 | 10 | $182.16 | Total: $1,821.60 |
| 1 | 25 | $154.33 | Total: $3,858.25 |
| 1 | 50 | $131.56 | Total: $6,578.00 |
| 1 | 100 | $113.85 | Total: $11,385.01 |
Overview
2',3'-cGAMP sodium (2'-3'-cyclic GMP-AMP sodium) is a second messenger in cellular innate immunity, catalyzed by cGAMP synthase (cGAS) under DNA binding conditions. It binds to STING to form a dimer, inducing the production and expression of interferon-? and other cytokines.
Chemical Properties
| Molecular Formula | C20H22N10Na2O13P2 |
| Molecular Weight | 718.37 |
| CAS Numbers | 2734858-36-5 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | OC1([H])[C@](OP(OC[C@](O[C@@H](N2C3=NC=NC(N)=C3N=C2)[C@@H]4O)([H])[C@@]4([H])O5)(O[Na])=O)([H])[C@H](N6C(NC(N)=NC7=O)=C7N=C6)O[C@]1([H])COP5(O[Na])=O |
Storage and Handling
0C Short Term, -20C Long Term
References
Guo X, et al. Cyclic GMP-AMP Ameliorates Diet-induced Metabolic Dysregulation and Regulates Proinflammatory Responses Distinctly from STING Activation. Sci Rep. 2017 Jul 25;7[1] 6355.