Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $328.95 | Total: $1,644.75 |
| 1 | 10 | $278.64 | Total: $2,786.40 |
| 1 | 25 | $236.07 | Total: $5,901.75 |
| 1 | 50 | $201.24 | Total: $10,062.00 |
| 1 | 100 | $174.15 | Total: $17,415.01 |
Overview
ABBV-CLS-484 (Osunprotafib) is a potent PTPN2 inhibitor with subnanomolar activity and antitumor activity that enhances T-cell anti-tumor immunity.ABBV-CLS-484 can be used for the treatment of neoplasms, esophageal cancer, and digestive disorders.
Chemical Properties
| Molecular Formula | C17H24FN3O4S |
| Molecular Weight | 385.45 |
| CAS Numbers | 2489404-97-7 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC(C)CCN[C@@H]1CCc2cc(O)c(N3CC(=O)NS3(=O)=O)c(F)c2C1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Philip R, et al. Protein tyrosine phosphatase inhibitors and methods of use thereof. WO2022056281A1.