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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $211.65 | Total: $1,058.25 |
| 1 | 10 | $179.28 | Total: $1,792.80 |
| 1 | 25 | $151.89 | Total: $3,797.25 |
| 1 | 50 | $129.48 | Total: $6,474.00 |
| 1 | 100 | $112.05 | Total: $11,205.00 |
Overview
ABT-963 is a potent and selective inhibitor of disubstituted pyridazinone cyclooxygenase-2 (LOX2) that dose-dependently reduces injury perception in a carrageenan model of nociceptive sensitization.ABT-963 is used in the study of arthritis.
Chemical Properties
| Molecular Formula | C22H22F2N2O5S |
| Molecular Weight | 464.48 |
| CAS Numbers | 266320-83-6 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=C1C(OCCC(O)(C)C)=C(C=NN1C2=CC=C(F)C(F)=C2)C3=CC=C(C=C3)S(=O)(=O)C |
Storage and Handling
0C Short Term, -20C Long Term
References
Harris RR, et al. ABT-963 [2-[3,4-difluoro-phenyl]-4-[3-hydroxy-3-methyl-butoxy]-5-[4-methanesulfonyl-pheny l]-2H-pyridazin-3-one], a highly potent and selective disubstituted pyridazinone cyclooxgenase-2 inhibitor. J Pharmacol Exp Ther. 2004 Dec;311[3] 904-12.