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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $64.60 | Total: $323.00 |
| 1 | 10 | $54.72 | Total: $547.20 |
| 1 | 25 | $46.36 | Total: $1,159.00 |
| 1 | 50 | $39.52 | Total: $1,976.00 |
| 1 | 100 | $34.20 | Total: $3,420.00 |
Overview
Kira8 (AMG-18) is a mono-selective IRE1? inhibitor that allosterically attenuates IRE1? RNase activity with an IC50 of 5.9 nM.
Chemical Properties
| Molecular Formula | C31H29ClN6O3S |
| Molecular Weight | 601.12 |
| CAS Numbers | 1630086-20-2 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cc1ccc2c(NS(=O)(=O)c3ccccc3Cl)cccc2c1Oc1ncccc1-c1ccnc(N[C@H]2CCCNC2)n1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Morita S, et al. Targeting ABL-IRE1? Signaling Spares ER-Stressed Pancreatic ? Cells to Reverse Autoimmune Diabetes. Cell Metab. 2017 Apr 4;25[4] 883-897.e8.