Categories
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $22.10 | Total: $110.50 |
| 1 | 10 | $18.72 | Total: $187.20 |
| 1 | 25 | $15.86 | Total: $396.50 |
| 1 | 50 | $13.52 | Total: $676.00 |
| 1 | 100 | $11.70 | Total: $1,170.00 |
Overview
AMG 579 is an efficacious and selective inhibitor of PDE10A (IC50 = 0.1 nM).
Chemical Properties
| Molecular Formula | C25H23N5O3 |
| Molecular Weight | 441.48 |
| CAS Numbers | 1227067-61-9 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC(=O)N1CCC(CC1)c1nccnc1Oc1ccc(cc1)C(=O)c1nc2ccccc2[nH]1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Hu E,et al. Discovery of clinical candidate 1-[4-[3-[4-[1H-benzo[d]imidazole-2-carbonyl]phenoxy]pyrazin-2-yl]piperidin-1-yl]ethanone [AMG 579], a potent, selective, and efficacious inhibitor of phosphodiesterase 10A [PDE10A]. J Med Chem. 2014 Aug 14;57[15] 6632-41.