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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $135.15 | Total: $675.75 |
| 1 | 10 | $114.48 | Total: $1,144.80 |
| 1 | 25 | $96.99 | Total: $2,424.75 |
| 1 | 50 | $82.68 | Total: $4,134.00 |
| 1 | 100 | $71.55 | Total: $7,155.00 |
Overview
Lisaftoclax (Bcl-2Bcl-xl inhibitor 1) is an oral dual inhibitor of Bcl-2 and Bcl-xl, with IC50 values of 2 nM and 5.9 nM for Bcl-2 and Bcl-xl, respectively. Lisaftoclax is used to treat chronic lymphocytic leukemia (CLL) by inhibiting the action of the BCL-2 protein, which promotes the death of leukemia cells.
Chemical Properties
| Molecular Formula | C45H48ClN7O8S |
| Molecular Weight | 882.42 |
| CAS Numbers | 2180923-05-9 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | [O-][N+](=O)c1cc(ccc1NC[C@H]1COCCO1)S(=O)(=O)NC(=O)c1ccc(cc1Oc1cnc2[nH]ccc2c1)N1CCN(CC2=C(CC3(CCC3)CC2)c2ccc(Cl)cc2)CC1 |
Storage and Handling
0C Short Term, -20C Long Term
References
WANG, Chia, et al. N-[PHENYLSULFONYL]BENZAMIDES AND RELATED COMPOUNDS AS BCL-2 INHIBITORS. Patent. WO2018027097A1.