Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
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- Stem Cell Research
- Alzheimer's Disease
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- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $107.95 | Total: $539.75 |
| 1 | 10 | $91.44 | Total: $914.40 |
| 1 | 25 | $77.47 | Total: $1,936.75 |
| 1 | 50 | $66.04 | Total: $3,302.00 |
| 1 | 100 | $57.15 | Total: $5,715.00 |
Overview
Lanabecestat (AZD3293) is a highly potent and highly permeable, orally active BACE1 inhibitor (Ki: 0.4 nM) that crosses the blood-brain barrier, Lanabecestat can be used for the study of neurological diseases like Alzheimer's disease.
Chemical Properties
| Molecular Formula | C26H28N4O |
| Molecular Weight | 412.53 |
| CAS Numbers | 1383982-64-6 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | COC1CCC2(Cc3ccc(cc3[C@@]22N=C(C)C(N)=N2)-c2cncc(c2)C#CC)CC1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Yao AY, et al. Bace1 Deletion in the Adult Reverses Epileptiform Activity and Sleep-wake Disturbances in AD Mice. J Neurosci. 2023 Aug 30;43[35] 6197-6211.