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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $153.85 | Total: $769.25 |
| 1 | 10 | $130.32 | Total: $1,303.20 |
| 1 | 25 | $110.41 | Total: $2,760.25 |
| 1 | 50 | $94.12 | Total: $4,706.00 |
| 1 | 100 | $81.45 | Total: $8,145.00 |
Overview
AZD-5672 is an antagonist of CCR5 with an IC50 of 0.32 nM. AZD-5672 inhibits hERG cardiac ion channel binding and P-gp-mediated digoxin transport with IC50s of 7.3 ?M and 32 ?M. AZD-5672 can be used in studies about rheumatoid arthritis.
Chemical Properties
| Molecular Formula | C32H38F2N2O5S2 |
| Molecular Weight | 632.78 |
| CAS Numbers | 780750-65-4 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CCN(C1CCN(CC[C@H](c2ccc(cc2)S(C)(=O)=O)c2cc(F)cc(F)c2)CC1)C(=O)Cc1ccc(cc1)S(C)(=O)=O |
Storage and Handling
0C Short Term, -20C Long Term
References
Elsby R, et al. The utility of in vitro data in making accurate predictions of human P-glycoprotein-mediated drug-drug interactions a case study for AZD5672. Drug Metab Dispos. 2011 Feb;39[2] 275-82.