Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $119.00 | Total: $595.00 |
| 1 | 10 | $100.80 | Total: $1,008.00 |
| 1 | 25 | $85.40 | Total: $2,135.00 |
| 1 | 50 | $72.80 | Total: $3,640.00 |
| 1 | 100 | $63.00 | Total: $6,300.00 |
Overview
Golcadomide (CC-99282) is a orally active CRBN E3 ligase modulator that induces interactions between CRBN and its neo-substrate, recruiting the target disease-causing proteins and the E3 ubiquitin ligase.Golcadomide is used in the study of hematologic malignancies.
Chemical Properties
| Molecular Formula | C28H30FN5O5 |
| Molecular Weight | 535.57 |
| CAS Numbers | 2379572-34-4 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | N(CC1=C(F)C=C(CN2CC(C2)N3CCOCC3)C=C1)C4=C5C(C(=O)N(C5=O)[C@@H]6C(=O)NC(=O)CC6)=CC=C4 |
Storage and Handling
0C Short Term, -20C Long Term
References
Fuchs O. Targeting cereblon in hematologic malignancies. Blood Rev. 2023 Jan;57 100994.