Categories
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- Protein Control Ligand
- Pathway Inhibitors
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- Nuclear Receptor Ligands
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- TNF Receptors
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $56.95 | Total: $284.75 |
| 1 | 10 | $48.24 | Total: $482.40 |
| 1 | 25 | $40.87 | Total: $1,021.75 |
| 1 | 50 | $34.84 | Total: $1,742.00 |
| 1 | 100 | $30.15 | Total: $3,015.00 |
Overview
CFT7455 (Cemsidomide) is an anti-cancer agent showing high affinity to the cereblon E3 ligase with a Kd of 0.9 nM. CFT7455 is an orally active degrader of zinc finger transcription factors Ikaros (IKZF1), and Aiolos (IKZF3).
Chemical Properties
| Molecular Formula | C28H27N3O4 |
| Molecular Weight | 469.53 |
| CAS Numbers | 2504235-67-8 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | [H][C@@]1(CCC(=O)NC1=O)N1C(=O)c2cccc3c(Cc4ccc(CN5CCOCC5)cc4)ccc1c23 |
Storage and Handling
0C Short Term, -20C Long Term
References
David Proia, et al. Advantageous therapies for disorders mediated by ikaros or aiolos. WO2022032132A1.