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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $103.70 | Total: $518.50 |
| 1 | 10 | $87.84 | Total: $878.40 |
| 1 | 25 | $74.42 | Total: $1,860.50 |
| 1 | 50 | $63.44 | Total: $3,172.00 |
| 1 | 100 | $54.90 | Total: $5,490.00 |
Overview
PF-05221304 (NSC-170984) is an orally active, liver-targeted inhibitor of acetyl-CoA carboxylase (ACC), a rate-limiting enzymes for fatty acid synthesis.
Chemical Properties
| Molecular Formula | C28H30N4O5 |
| Molecular Weight | 502.56 |
| CAS Numbers | 1370448-25-1 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=C1CC2(CC3=C1N(C(C)C)N=C3)CCN(C(=O)C=4C=C(N=C(OC)C4)C5=CC=C(C(O)=O)C=C5)CC2 |
Storage and Handling
0C Short Term, -20C Long Term
References
Ross T T , Crowley C , Kelly K L , et al. Acetyl-CoA Carboxylase Inhibition Improves Multiple Dimensions of NASH Pathogenesis in Model Systems[J]. Cellular and Molecular Gastroenterology and Hepatology, 2020, 10[4].