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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $27.20 | Total: $136.00 |
| 1 | 10 | $23.04 | Total: $230.40 |
| 1 | 25 | $19.52 | Total: $488.00 |
| 1 | 50 | $16.64 | Total: $832.00 |
| 1 | 100 | $14.40 | Total: $1,440.00 |
Overview
GS143 is a selective I?B? ubiquitination inhibitor with an IC50 of 5.2 ?M for SCF?TrCP1-mediated I?B? ubiquitylation. It suppresses NF-?B activation and transcription of target genes without inhibiting proteasome activity. GS143 has anti-asthm[atic] properties.
Chemical Properties
| Molecular Formula | C28H19FN2O4 |
| Molecular Weight | 466.46 |
| CAS Numbers | 916232-21-8 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | OC(=O)c1ccc(cc1)N1N=C(Cc2ccccc2)C(=Cc2ccc(o2)-c2ccccc2F)C1=O |
Storage and Handling
0C Short Term, -20C Long Term
References
Rashmi BS, Gayathri D. Molecular characterization of gluten hydrolysing Bacillus sp. and their efficacy and biotherapeutic potential as probiotics using Caco-2 cell line. J Appl Microbiol. 2017 Sep;123[3] 759-772. doi 10.1111jam.13517. Epub 2017 Aug 4. PubMed PMID 28637081.