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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $87.55 | Total: $437.75 |
| 1 | 10 | $74.16 | Total: $741.60 |
| 1 | 25 | $62.83 | Total: $1,570.75 |
| 1 | 50 | $53.56 | Total: $2,678.00 |
| 1 | 100 | $46.35 | Total: $4,635.00 |
Overview
(EZ)-BCI (NSC-150117), a dual-specificity phosphatase 6 (DUSP6) inhibitor with anti-inflammatory properties, reduces LPS-induced inflammatory mediators and ROS production in macrophage cells by activating the Nrf2 signaling axis and inhibiting the NF-?B pathway.
Chemical Properties
| Molecular Formula | C22H23NO |
| Molecular Weight | 317.42 |
| CAS Numbers | 15982-84-0 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=C1C(=Cc2ccccc2)C(NC2CCCCC2)c2ccccc12 |
Storage and Handling
0C Short Term, -20C Long Term
References
Zhang F, et al. DUSP6 Inhibitor [EZ]-BCI Hydrochloride Attenuates Lipopolysaccharide-Induced Inflammatory Responses in Murine Macrophage Cells via Activating the Nrf2 Signaling Axis and Inhibiting the NF-?B Pathway. Inflammation. 2019 Apr;42[2] 672-681.