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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $114.75 | Total: $573.75 |
| 1 | 10 | $97.20 | Total: $972.00 |
| 1 | 25 | $82.35 | Total: $2,058.75 |
| 1 | 50 | $70.20 | Total: $3,510.00 |
| 1 | 100 | $60.75 | Total: $6,075.00 |
Overview
Pep2m, myristoylated acetate is a Cell-permeable, myristoylated form of pep2m. Peptide inhibitor of the interaction between the C-terminus of the GluA2 (AMPA receptor) subunit and N-ethylmaleimide-sensitive fusion protein (NSF), a protein that regulates AMPA receptor function. Reduces postsynaptic currents in CA1 neurons, AMPA-mediated currents in cultured hippocampal neurons and AMPA receptor surface expression.
Chemical Properties
| Molecular Formula | C65H122N18O16S |
| Molecular Weight | 1443.96 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CCCCCCCCCCCCCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)N)C(=O)O.CC(=O)O |
Storage and Handling
0C Short Term, -20C Long Term
References
Nishimune et al [1998] NSF binding to GluR2 regulates synaptic transmission. Neuron 21 87 PMID 9697854